Guinea Pigs

Find out how guinea pigs have been used for science in NZ.

Lovingly called cavies by their fans (from their Latin name Cavia porcellus), guinea pigs are known as easy-to-care-for companion animals. Sadly, these small, cute rodents are used for science in NZ, where they rarely make it out alive.

In 2021, 3,431 guinea pigs were used for science in NZ. Most (97%) were killed.

Sad fact: The percentage of guinea pigs who were killed after or during use has never been below 91% since 2010.1

Guinea pigs in NZ have been used for:
  • Testing animal vaccines - according to MPI, guinea pigs are used in batch testing of animal vaccines as a regulatory requirement to demonstrate potency.
  • The production of biological agents.
  • Veterinary Research, including research examining reactions to anaesthesia.
  • Drug research.
  • Medical research, including trying to model humans in research relating to pre-term labour and birth, dietary influence on foetus development and milk composition, hearing, balance, vision, healing and secondary infections.
  • Teaching.
  • Basic biological research, including examining how intestines move and hearts function and how eyes and muscles develop.

Places that use guinea pigs for science in NZ include private companies, universities, and polytechnics.

Most guinea pigs used for science in NZ are sourced from breeding units. They are also obtained from commercial and public sources.

Discover real-life examples of how guinea pigs have been used in NZ below!

Testing nerve reactions to electric stimulation

Young guinea pigs were bled to death. Specific nerves were removed and experimented on.

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Questioning vets on pain management

Veterinarians completed a questionnaire regarding pain and pain management in rabbits and guinea pigs.

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Studying short-sightedness

Guinea pigs had one eye covered for two weeks before increasing their eye pressure surgically and kill them.

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Measuring nerve reactions to gases

Guinea pigs were anaesthetised, and their windpipe and blood vessels were cannulated. They were exposed to different gases and cyanide while measuring breathing and nerve activity.

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Studying how anaesthesia affects breathing and heart

Guinea pigs were put in airtight chambers to test the effects of low oxygen. Some were surgically fitted with tubing so blood samples could be taken during the tests. In the end, all were killed.

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Testing how heart calcium metabolism is different in species

Guinea pigs and rats were decapitated, and their hearts were quickly removed to study them.

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Testing a new tuberculosis vaccine

A new tuberculosis vaccine was tested by injecting guinea pigs with the bacteria, either with or without prior vaccination. After several weeks, all were killed.

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Harvesting testicles for studies

Male guinea pigs were killed with CO2 to remove their testicles for experiments.

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Testing how oxytocin injections cause contractions

Pregnant guinea pigs were surgically implanted with electrodes on or near the uterus. They were injected with oxytocin in specific doses and timeframes, and the effects were measured.

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Killing pregnant guinea pigs for tissue cultures

Pregnant guinea pigs were anaesthetised at specific time points of their pregnancy, including during labour, to then remove the uterus for tissue culture experiments.

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Studying compensation after inner ear destruction

Guinea pigs were anaesthetised, and their inner ear was destroyed with a drill. Videos were made for over two days of their balance recovery.

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Confirming the correlation of energy storage and stress in the inner ear fluid

Guinea pigs were anaesthetised and artificially ventilated. Ear fluid samples were taken through a hole in the skull, while exposing them to noise or lack of oxygen.

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Testing influences on the rate of a dissected heart

Albino guinea pigs were anaesthetised and dissected before they were killed.

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Comparing natural and genetically altered tuberculosis strains

Guinea pigs were infected with tuberculosis strains after being injected with bacterial proteins beforehand. In the end, all guinea pigs were killed and dissected.

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Comparing effects of anaesthetics on breathing and heart rate

Guinea pigs, rabbits and rats were anaesthetised, and a tube was put into their windpipe through the neck. They were made to breathe anaesthetic gas.

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